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Base by Base

Base by Base explores advances in genetics and genomics, with a focus on gene-disease associations, variant interpretation, protein structure, and insights from exome and genome sequencing. Each episode breaks down key studies and their clinical...more

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Latest Episodes

️ 46: Pan-Epitranscriptomic Control — How tRNA and m6A Interact to Regulate mRNA Decay

Episode 46

June 14, 2025

️ 46: Pan-Epitranscriptomic Control — How tRNA and m6A Interact to Regulate mRNA Decay

️ Episode 46: Pan-Epitranscriptomic Control — How tRNA and m6A Interact to Regulate mRNA Decay In this episode of Base by Base, we delve...

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00:20:34

️ 45: Probing Nucleolar Mechanics — RNA-Dependent Viscoelasticity of Nucleolar Subcompartments

Episode 45

June 12, 2025

️ 45: Probing Nucleolar Mechanics — RNA-Dependent Viscoelasticity of Nucleolar Subcompartments

️ Episode 45: Probing Nucleolar Mechanics — RNA-Dependent Viscoelasticity of Nucleolar Subcompartments In this episode of Base por Base, we delve into a groundbreaking...

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00:20:53

️ 44: Proofreading Precision — Unveiling the Cryo-EM Mechanism of Human DNA Polymerase ε Holoenzyme

Episode 44

June 12, 2025

️ 44: Proofreading Precision — Unveiling the Cryo-EM Mechanism of Human DNA Polymerase ε Holoenzyme

️ Episode 44: Proofreading Precision — Unveiling the Cryo-EM Mechanism of Human DNA Polymerase ε Holoenzyme In this episode of Base per Base, we...

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00:19:02

️ 43: Personalized Molecular Signatures of Insulin Resistance and Type 2 Diabetes

Episode 43

June 11, 2025

️ 43: Personalized Molecular Signatures of Insulin Resistance and Type 2 Diabetes

️ Episode 43: Personalized Molecular Signatures of Insulin Resistance and Type 2 Diabetes In this episode of Base by Base, we explore the groundbreaking...

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00:19:33

️ 42: Amino Acids Catalyse RNA Formation — Unlocking Prebiotic Cross-Catalysis

Episode 42

June 11, 2025

️ 42: Amino Acids Catalyse RNA Formation — Unlocking Prebiotic Cross-Catalysis

️ Episode 42: Amino Acids Catalyse RNA Formation — Unlocking Prebiotic Cross-Catalysis In this episode of Base por Base, we delve into the groundbreaking...

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00:23:35

️ 41: Public Preferences for Genomic Newborn Screening in Australia — Insights from Discrete Choice Experiments

Episode 41

June 10, 2025

️ 41: Public Preferences for Genomic Newborn Screening in Australia — Insights from Discrete Choice Experiments

️ Episode 41: Public Preferences for Genomic Newborn Screening in Australia — Insights from Discrete Choice Experiments In this episode of Base by Base,...

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00:18:43

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