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Base by Base

Base by Base explores advances in genetics and genomics, with a focus on gene-disease associations, variant interpretation, protein structure, and insights from exome and genome sequencing. Each episode breaks down key studies and their clinical...more

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Latest Episodes

️ 52: Human Genetic Variation Reveals FCRL3 as a Lymphocyte Receptor for Yersinia pestis

Episode 52

June 22, 2025

️ 52: Human Genetic Variation Reveals FCRL3 as a Lymphocyte Receptor for Yersinia pestis

️ Episode 52: Human Genetic Variation Reveals FCRL3 as a Lymphocyte Receptor for Yersinia pestis In this episode of Base by Base, we dive...

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00:16:43

️ 51: Diagnosing the Undiagnosed — A Phenotype-Driven Pipeline for Mitochondrial DNA Discovery

Episode 51

June 21, 2025

️ 51: Diagnosing the Undiagnosed — A Phenotype-Driven Pipeline for Mitochondrial DNA Discovery

️ Episode 51: Diagnosing the Undiagnosed — A Phenotype-Driven Pipeline for Mitochondrial DNA Discovery In this episode of Base by Base, we dive into...

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00:17:38

️ 50: The Microbiome for Clinicians — Bridging Research and Practice

Episode 50

June 19, 2025

️ 50: The Microbiome for Clinicians — Bridging Research and Practice

️ Episode 50: The Microbiome for Clinicians — Bridging Research and Practice In this episode of Base by Base, we explore a Perspective article...

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00:17:57

️ 49: Chitin as a Reservoir for Horizontal Gene Transfer — Environmental DNA Adsorption and Natural Transformation in Vibrio cholerae

Episode 49

June 18, 2025

️ 49: Chitin as a Reservoir for Horizontal Gene Transfer — Environmental DNA Adsorption and Natural Transformation in Vibrio cholerae

️ Episode 49: Chitin as a Reservoir for Horizontal Gene Transfer — Environmental DNA Adsorption and Natural Transformation in Vibrio cholerae In this episode...

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00:22:59

️ 48: Mainstreaming Genetic Testing — A Conceptual Framework for Expanding Genomic Medicine

Episode 48

June 16, 2025

️ 48: Mainstreaming Genetic Testing — A Conceptual Framework for Expanding Genomic Medicine

️ Episode 48: Mainstreaming Genetic Testing — A Conceptual Framework for Expanding Genomic Medicine In this episode of Base by Base, we explore an...

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00:16:11

️ 47: Selectivity and Promiscuity — Decoding the Human Chemokine-GPCR Network

Episode 47

June 16, 2025

️ 47: Selectivity and Promiscuity — Decoding the Human Chemokine-GPCR Network

️ Episode 47: Selectivity and Promiscuity — Decoding the Human Chemokine-GPCR Network In this episode of Base by Base, we explore a systems-level framework...

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00:22:38

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