Podcast Cover

Base by Base

Base by Base explores advances in genetics and genomics, with a focus on gene-disease associations, variant interpretation, protein structure, and insights from exome and genome sequencing. Each episode breaks down key studies and their clinical...more

Hosted by

Latest Episodes

144: Revised time estimation of the ancestral human chromosome 2 fusion

Episode 144

September 21, 2025

144: Revised time estimation of the ancestral human chromosome 2 fusion

️ Episode 144: Revised time estimation of the ancestral human chromosome 2 fusion In this episode of PaperCast Base by Base, we explore a...

Play

00:17:10

143: The genetic history of the Southern Caucasus: 5,000 years of continuity despite high mobility

Episode 143

September 20, 2025

143: The genetic history of the Southern Caucasus: 5,000 years of continuity despite high mobility

️ Episode 143: The genetic history of the Southern Caucasus: 5,000 years of continuity despite high mobility In this episode of PaperCast Base by...

Play

00:18:56

142: Specifications of the ACMG/AMP Guidelines for PALB2 Variant Interpretation

Episode 142

September 19, 2025

142: Specifications of the ACMG/AMP Guidelines for PALB2 Variant Interpretation

️ Episode 142: Specifications of the ACMG/AMP Guidelines for PALB2 Variant Interpretation In this episode of PaperCast Base by Base, we explore how the...

Play

00:16:35

141: RetiGene, a comprehensive gene atlas for inherited retinal diseases

Episode 141

September 18, 2025

141: RetiGene, a comprehensive gene atlas for inherited retinal diseases

️ Episode 141: RetiGene, a comprehensive gene atlas for inherited retinal diseases In this episode of PaperCast Base by Base, we explore RetiGene, an...

Play

00:26:12

140: Landscapes of missense variant impact for human superoxide dismutase 1

Episode 140

September 17, 2025

140: Landscapes of missense variant impact for human superoxide dismutase 1

️ Episode 140: Landscapes of missense variant impact for human superoxide dismutase 1 In this episode of PaperCast Base by Base, we explore a...

Play

00:20:18

139: MosCoverY: A new method to estimate mosaic loss of Y chromosome from sequencing coverage data

Episode 139

September 16, 2025

139: MosCoverY: A new method to estimate mosaic loss of Y chromosome from sequencing coverage data

️ Episode 139: MosCoverY: A new method to estimate mosaic loss of Y chromosome from sequencing coverage data In this episode of PaperCast Base...

Play

00:14:03

Previous Next