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Base by Base

Base by Base explores advances in genetics and genomics, with a focus on gene-disease associations, variant interpretation, protein structure, and insights from exome and genome sequencing. Each episode breaks down key studies and their clinical...more

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Latest Episodes

️ 98: Cell Marker Accordion: Interpretable Single-Cell and Spatial Omics Annotation in Health and Disease

Episode 98

August 06, 2025

️ 98: Cell Marker Accordion: Interpretable Single-Cell and Spatial Omics Annotation in Health and Disease

️ Episode 98: Cell Marker Accordion: Interpretable Single-Cell and Spatial Omics Annotation in Health and Disease In this episode of PaperCast Base by Base,...

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00:19:20

️ 97: Pancreatic Cancer Genomics: Insights from the COMPASS Trial

August 05, 2025

️ 97: Pancreatic Cancer Genomics: Insights from the COMPASS Trial

️ Episode 97: Pancreatic Cancer Genomics: Insights from the COMPASS Trial In this episode of PaperCast Base by Base, we explore how integrated whole...

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00:21:43

️ 96: Early Cerebrospinal Fluid Proteomic Changes in Down Syndrome and Alzheimer’s Disease

August 04, 2025

️ 96: Early Cerebrospinal Fluid Proteomic Changes in Down Syndrome and Alzheimer’s Disease

️ Episode 96: Early Cerebrospinal Fluid Proteomic Changes in Down Syndrome and Alzheimer’s Disease In this episode of PaperCast Base by Base, we explore...

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00:16:39

️ 95: Mitochondria on the Move: Biotechnological Strategies for Transfer and Transplantation

Episode 95

August 03, 2025

️ 95: Mitochondria on the Move: Biotechnological Strategies for Transfer and Transplantation

️ Episode 95: Mitochondria on the Move: Biotechnological Strategies for Transfer and Transplantation In this episode of PaperCast Base by Base, we explore recent...

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00:19:10

️ 94: Intraindividual Epigenetic Heterogeneity in Advanced Prostate Cancer

Episode 94

August 02, 2025

️ 94: Intraindividual Epigenetic Heterogeneity in Advanced Prostate Cancer

️ Episode 94: Intraindividual Epigenetic Heterogeneity in Advanced Prostate Cancer In this episode of PaperCast Base by Base, we explore how integrated DNA methylation,...

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00:20:29

️ 93: Neuroinvasive and Pulmonary Virulence of H5N1 Clade 2.3.4.4b Genotype B3.13

Episode 93

August 01, 2025

️ 93: Neuroinvasive and Pulmonary Virulence of H5N1 Clade 2.3.4.4b Genotype B3.13

️ Episode 93: Neuroinvasive and Pulmonary Virulence of H5N1 Clade 2.3.4.4b Genotype B3.13 In this episode of PaperCast Base by Base, we explore how...

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00:19:01

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