Latest Episodes
Episode 467
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October 18, 2026
467: Finding mutations carried by fewer than 1 in 100 cells
Jang Y et al., The American Journal of Human Genetics - Every cell in the body picks up its own small set of DNA...
00:18:37
Episode 466
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October 16, 2026
466: A quieter MECP2 switch and the male bias in autism
Meyer-Schuman R et al., The American Journal of Human Genetics - Autism is diagnosed about four times more often in male individuals than in...
00:18:45
Episode 465
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October 11, 2026
465: When a lysosomal storage gene shows up only in the retina
Lin et al., The American Journal of Human Genetics - Bi-allelic variants in IDUA classically cause mucopolysaccharidosis type I, a lysosomal storage disorder that...
00:20:03
Episode 464
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October 06, 2026
464: Burning fat while sparing muscle on GLP-1 drugs, in mice
Thorne et al., Proceedings of the National Academy of Sciences - GLP-1 receptor agonists such as semaglutide produce large weight loss, but part of...
00:18:20
Episode 463
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October 04, 2026
463: Why brain traits leave faint, common genetic signals
Zhu et al., Proceedings of the National Academy of Sciences - Genome-wide studies of schizophrenia and other psychiatric disorders find hundreds of hits, yet...
00:18:21
Episode 462
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September 30, 2026
462: A vessel gene tied to AMD dims low-light vision in mice
Cheng et al., Proceedings of the National Academy of Sciences - Genome-wide studies have found dozens of risk loci for age-related macular degeneration, but...
00:20:10