Latest Episodes
Episode 472
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November 02, 2026
472: 490,319 genomes that fill the gaps in genetic studies
Wienbrandt L et al., Nature Genetics - Most genetic studies read only a fraction of the genome and infer the rest from a reference...
00:17:57
Episode 471
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October 30, 2026
471: How cancer treatment picks winners among mutant clones in the normal esophagus
Fowler J et al., Nature Genetics - Normal esophageal lining is a patchwork of mutant clones that compete for space as we age. This...
00:17:54
Episode 470
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October 29, 2026
470: The hidden swaps CRISPR leaves between sister chromosomes
Chovanec P et al., eLife - When CRISPR/Cas9 cuts DNA, editing is usually judged by the small insertions and deletions left at the break....
00:17:23
Episode 469
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October 27, 2026
469: What the shape of a face reveals about cleft risk
Herrick N et al., Human Genetics and Genomics Advances - Orofacial clefts are among the most common birth defects, affecting about 1 in 700...
00:18:17
Episode 468
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October 25, 2026
468: When a splicing factor breaks in different ways
Lisfeld J et al., The American Journal of Human Genetics - SRSF3 is an essential splicing factor, one of the serine/arginine-rich proteins that help...
00:17:30
Episode 467
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October 18, 2026
467: Finding mutations carried by fewer than 1 in 100 cells
Jang Y et al., The American Journal of Human Genetics - Every cell in the body picks up its own small set of DNA...
00:18:37