Latest Episodes
Episode 397
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June 20, 2026
397: SciPhy: Bayesian phylogenetics for sequential genetic lineage tracing
Seidel et al., Nature Communications - SciPhy is a BEAST2-integrated Bayesian framework that models sequential CRISPR‑based insertion edits to jointly infer time-scaled single-cell lineage...
00:23:27
Episode 396
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June 18, 2026
396: Physical homology recognition between DNA duplexes
Stannard A et al., Proceedings of the National Academy of Sciences (PNAS) - This episode summarizes a PNAS study that uses a FRET-responsive DNA...
00:23:26
Episode 395
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June 18, 2026
395: Extended sequence context shapes mutational bias in Escherichia coli
Green R et al., PNAS - Collating >100,000 base-pair substitutions from 32 mutation-accumulation experiments, this study shows that sequence context well beyond adjacent bases...
00:22:43
Episode 394
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June 17, 2026
394: Benchmarking LLMs for cfRNA biomarker discovery
Gaudio HA et al., Nature Communications - This episode examines a systematic benchmark of six commercial large language models applied to plasma cell-free RNA...
00:22:34
Episode 393
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June 17, 2026
393: Hidden Resistance: tNGS Reveals Rifampicin and Bedaquiline Resistance in Eswatini
Vambe D et al., Nature Communications - This study reports the programmatic introduction of targeted next-generation sequencing (tNGS) in Eswatini and shows that tNGS...
00:21:20
Episode 392
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June 12, 2026
392: GWAS of Cocaine Self-Administration in Heterogeneous Stock Rats
Lara MK et al et al., Nature Communications - Large GWAS in 836 outbred HS rats identifies six loci linked to cocaine self-administration traits,...
00:23:23