Latest Episodes
Episode 259
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January 14, 2026
259: Ku filaments that hold DNA together
Zahid S et al., Nat Commun - Cryo-EM and biophysical analyses show Mycobacterium tuberculosis Ku assembles into DNA-bound oligomeric filaments that synapse DNA ends...
00:17:49
Episode 258
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January 13, 2026
258: Correcting GC bias in metagenomes
Holcik L et al., Genomic GC bias correction improves species abundance estimation from metagenomic data. Nature Communications - GuaCAMOLE is an alignment-free algorithm that...
00:17:09
Episode 257
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January 12, 2026
257: PSMC5: proteasomes, immunity and neurodevelopment
Küry S et al., Nat Commun - This study describes 26 distinct PSMC5 variants in 44 individuals and demonstrates that PSMC5 loss impairs proteasome...
00:18:05
Episode 256
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January 11, 2026
256: Compartmental control of VSG silencing
Antunes et al., Chromosome compartment assembly is essential for subtelomeric gene silencing in trypanosomes. Nat Commun ( - The study shows that spatial segregation...
00:18:52
Episode 255
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January 10, 2026
255: Lipids, Ions and the AE1 Elevator
Chen T et al., Nat Commun - Cryo-EM structures, uptake assays, and molecular dynamics show that PIP2 lipids bind at the AE1 dimer interface...
00:19:08
Episode 254
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January 09, 2026
254: Rescuing the replisome at a nick
Winterhalter et al., Rescuing the bacterial replisome at a nick requires recombinational repair and helicase reloading. Nat Commun ( - Cas9 nickases in Bacillus...
00:19:52