Latest Episodes
Episode 437
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August 09, 2026
437: Cell villages and Dirichlet modeling map human cell fitness genetics
Hanson C et al., The American Journal of Human Genetics - Hanson et al. combine pooled multi-donor human neural progenitor cell "villages" with Townlet,...
00:28:03
Episode 436
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August 08, 2026
436: KIAP4 and the ARND family: building the Leishmania adhesion plaque
Owino BO et al., PNAS - Using TurboID proximity proteomics and microscopy, researchers identify KIAP4 as the canonical member of a conserved Adhesion Related...
00:24:51
Episode 435
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August 07, 2026
435: E. coli TGT binds two tRNAs — cryo-EM reveals dual engagement
Ember M et al., PNAS - This episode examines a cryo-EM study of Escherichia coli tRNA-guanine transglycosylase (TGT) that solves the enzyme structure and...
00:19:03
Episode 434
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August 06, 2026
434: High‑coverage genomes recast Japan's prehistoric demography
Ishiya K et al., PNAS - This episode examines a PNAS study that reports two high-coverage ancient human genomes from mainland Japan (an Initial...
00:27:07
Episode 433
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July 23, 2026
433: Lactate, HSP90α and the Mitochondrial Switch
Wu G et al., Proceedings of the National Academy of Sciences - This episode examines a PNAS study that identifies site-specific lactylation of HSP90α...
00:23:55
Episode 432
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July 23, 2026
432: Echovirus 18: Capsid opening releases the genome
Mukhamedova L et al., Proceedings of the National Academy of Sciences - Using cryo-electron tomography and single-particle cryo-EM of infected Cos-7 cells, the authors...
00:18:29