Latest Episodes
Episode 265
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January 20, 2026
265: ANTSR lncRNA and the conserved multiallelic sex-determining locus across Aculeata
Yu C et al., Proc. Natl. Acad. Sci. U.S.A - Genetic mapping and comparative genomics show the lncRNA ANTSR multiallelic locus in Aculeata directs...
00:17:51
Episode 264
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January 19, 2026
264: Single-TF rejuvenation: EZH2, E2F3, STAT3, ZFX identified by TRDP/Perturb-seq rejuvenate human fibroblasts and mouse liver
Sengstack J et al., Proc. Natl. Acad. Sci. U.S.A - TRDP with Perturb-seq in human fibroblasts found that manipulating TFs (EZH2, E2F3, STAT3, ZFX)...
00:19:44
Episode 263
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January 18, 2026
263: Bifacial γPNA triplets target rCUG repeats and displace MBNL1 in Myotonic Dystrophy type 1
Perera J et al., R., Thadke S. A., Thrikawala S. W., Wilson W. D., Tan K. W. R., Chand N. Z. W., Phan A....
00:20:24
Episode 262
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January 17, 2026
262: Human Langerhans cells reprogrammed by tick saliva (CXCR4/CCR7 migration and IDO1/IRF4 tolerance)
Strobl et al., & Stary, G. Human epidermal Langerhans cells induce tolerance and hamper T cell function upon tick-borne pathogen transmission. Nature Communications -...
00:21:40
Episode 261
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January 16, 2026
261: MHz-XPCS reveals anomalous ferritin diffusion and nanoscale cage trapping
Girelli et al., Coherent X-rays reveal anomalous molecular diffusion and cage effects in crowded protein solutions. Nat Commun ( - MHz-XPCS of ferritin solutions...
00:16:20
Episode 260
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January 15, 2026
260: TSS hypermutability in human germline linked to RNAP II stalling, R-loops and early embryonic mosaics
Cortés Guzmán M et al., Nat Commun - Human germline transcription start sites show a hotspot of non-CpG variants driven by the early embryonic...
00:16:09