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Base by Base

Base by Base explores advances in genetics and genomics, with a focus on gene-disease associations, variant interpretation, protein structure, and insights from exome and genome sequencing. Each episode breaks down key studies and their clinical...more

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Latest Episodes

106: Decoding Brain Maps for Pharmacotranscriptomics

Episode 106

August 14, 2025

106: Decoding Brain Maps for Pharmacotranscriptomics

️ Episode 106: Decoding Brain Maps for Pharmacotranscriptomics In this episode of PaperCast Base by Base, we explore a Nature Communications study, that introduces...

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00:19:25

105: Genome-level Selection as a Universal Marker of Cancer Therapy Resistance

Episode 105

August 13, 2025

105: Genome-level Selection as a Universal Marker of Cancer Therapy Resistance

️ Episode 105: Genome-level Selection as a Universal Marker of Cancer Therapy Resistance In this episode of PaperCast Base by Base, we explore groundbreaking...

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00:18:28

104: Cross-population GWAS and proteomics improve risk prediction and reveal mechanisms in atrial fibrillation

Episode 104

August 12, 2025

104: Cross-population GWAS and proteomics improve risk prediction and reveal mechanisms in atrial fibrillation

Episode 104: Cross-population GWAS and proteomics improve risk prediction and reveal mechanisms in atrial fibrillation In this episode of PaperCast Base by Base, we...

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00:16:56

103: Genome Sequencing Forecasts Outcomes After Congenital Cardiac Surgery

Episode 103

August 11, 2025

103: Genome Sequencing Forecasts Outcomes After Congenital Cardiac Surgery

️ Episode 103: Genome Sequencing Forecasts Outcomes After Congenital Cardiac Surgery In this episode of PaperCast Base by Base, we explore how large-scale exome...

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00:17:56

102: Clinical Impact of Pharmacogenetic Risk Variants in a Large Chinese Cohort

Episode 102

August 10, 2025

102: Clinical Impact of Pharmacogenetic Risk Variants in a Large Chinese Cohort

Episode 102: Clinical Impact of Pharmacogenetic Risk Variants in a Large Chinese Cohort In this episode of PaperCast Base by Base, we explore how...

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00:14:38

101: JAK2 Inhibition Selects RAS-Mutant Clones in Myelofibrosis

Episode 101

August 09, 2025

101: JAK2 Inhibition Selects RAS-Mutant Clones in Myelofibrosis

️Episode 101: JAK2 Inhibition Selects RAS-Mutant Clones in Myelofibrosis In this episode of PaperCast Base by Base, we explore how JAK2 inhibition with ruxolitinib...

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00:18:25

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