Latest Episodes
Episode 390
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June 09, 2026
390: Daunorubicin, Mutual Destruction, and Layered Antiphage Defense
Gätgens C et al., PNAS - This episode examines how DNA-intercalating molecules like daunorubicin block bacteriophage infection at an early stage, causing an abortive-infection-like...
00:22:59
Episode 389
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June 09, 2026
389: Crotonylation impedes c-Myc oncogenic activity
PNAS - This study identifies crotonylation as a posttranslational modification of c-Myc that reduces its transcriptional and oncogenic activity. Key lysines K289 and K298...
00:25:28
Episode 388
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June 09, 2026
388: Base by Base | Episode 388 — In situ CAR‑macrophage alleviates liver fibrosis
Huang X et al., Proceedings of the National Academy of Sciences (PNAS) - This episode summarizes a PNAS study reporting CD163‑targeted lipid nanoparticles that...
00:21:01
Episode 387
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June 09, 2026
387: Homotypic Dengue Reinfections and Long-Term Antibody Decay
Andrade J et al., PNAS - Analysis of three long-term cohorts in the Philippines and Thailand shows antibody titers wane over years and that...
00:21:36
Episode 386
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June 05, 2026
386: Genome Doubling and the Bioeconomy
Peeters MKR et al., Proceedings of the National Academy of Sciences (PNAS) - A perspective outlining how genome doubling (polyploidy) reshapes genomes, phenotypes, and...
00:24:26
Episode 385
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June 04, 2026
385: Growth under Pressure: Polyploidy Induced by Stress
Sarabia Olivera L et al., PNAS - A perspective that surveys how diverse stresses trigger whole‑genome doubling (polyploidy) across fungi, plants, and animals, outlines...
00:24:49