Latest Episodes
Episode 336
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April 07, 2026
336: Measuring disease likelihood in genomic ascertainment
Sapp JC et al., The American Journal of Human Genetics - A longitudinal study of recipients of medically actionable secondary genomic findings develops a...
00:24:29
Episode 335
•
April 05, 2026
335: Altai Neandertal Genome Reveals Deep Population Structure
Massilania D et al., PNAS - We summarize a PNAS study reporting a ~37× genome from a ~110,000-year-old male Neandertal (Denisova 17) from Denisova...
00:23:54
Episode 334
•
April 05, 2026
334: LINE-1 Recombination with Diverse RNAs
Law C-T et al., Cell Genomics - Law and Burns introduce TiMEstamp, a comparative-genomics pipeline that dates LINE-1 insertions from multiple sequence alignments and...
00:21:38
Episode 333
•
April 04, 2026
333: Holistic determination of cfDNA ends
Jiang P et al., Cell Genomics - This episode reviews a Cell Genomics study that uses ssDNA '2-end' and novel '4-end' sequencing to profile...
00:24:43
Episode 333
•
April 04, 2026
333: Holistic determination of cfDNA ends
Jiang P et al., Cell Genomics - This episode reviews a Cell Genomics study that uses ssDNA '2-end' and novel '4-end' sequencing to profile...
Episode 332
•
April 02, 2026
332: When Chromatin Filters Force: Age, AP-1, and Fibroblast Mechanotransduction
Liao Y et al., PNAS - Human dermal fibroblasts from young and old donors were embedded in 3D collagen and exposed to mechanical tension...
00:22:31