Latest Episodes
Episode 254
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January 09, 2026
254: Rescuing the replisome at a nick
Winterhalter et al., Nature Communications - Cas9 nickases in Bacillus subtilis show that single-strand nicks in either template strand arrest DNA replication, create single-end...
00:19:52
Episode 253
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January 08, 2026
253: Nap1 and histone acetylation tune chromatin condensates
Gao J et al., Nature Communications - H4 tail lysine residues drive liquid-liquid phase separation of 12‑mer nucleosome arrays, while H3 tail acetylation and...
00:20:26
Episode 252
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January 07, 2026
252: Keratinocytes to cSCC: genetic steps
Deivendran D et al., Nature Communications, doi:10.1038/s41467-025-65687-y - Single-cell and spatial multi-omic profiling maps the genetic and transcriptional changes from normal keratinocytes through actinic...
00:18:13
Episode 251
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January 06, 2026
251: MuSCs, laminin-α2 and LAMA2 MD
McGowan TJ et al., Nature Communications, doi:10.1038/s41467-025-65703-1 - Activated muscle stem cells express and secrete laminin-α2 to remodel their niche, and loss of MuSC-derived...
00:19:00
Episode 250
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January 05, 2026
250: CIP2A–TOPBP1: Mitotic repair via MiDAS and MMEJ
Nieminuszczy J et al., Nature Communications, doi:10.1038/s41467-025-65594-2 - This study shows the CIP2A-TOPBP1 complex coordinates two mitotic double-strand break repair pathways, MiDAS and MMEJ,...
00:18:16
Episode 249
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January 04, 2026
249: PCM1 links centrosome asymmetry to endosome dynamics
Zhao X et al., Nature Communications - In developing neural progenitors PCM1 localizes to the mother centrosome and to Notch ligand-containing endosomes, promoting Par-3/dynein...
00:20:40