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Base by Base

Base by Base explores advances in genetics and genomics, with a focus on gene-disease associations, variant interpretation, protein structure, and insights from exome and genome sequencing. Each episode breaks down key studies and their clinical...more

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Latest Episodes

️ 90: Variable and Interactive Effects of Sex, APOE ε4 and TREM2 on Tau Deposition

Episode 90

July 29, 2025

️ 90: Variable and Interactive Effects of Sex, APOE ε4 and TREM2 on Tau Deposition

️ Episode 90: Variable and Interactive Effects of Sex, APOE ε4 and TREM2 on Tau Deposition In this episode of PaperCast Base by Base,...

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00:15:57

️ 89: Decoding the Genetics of Smell: Sex-Specific Variants in Olfactory Identification

Episode 89

July 28, 2025

️ 89: Decoding the Genetics of Smell: Sex-Specific Variants in Olfactory Identification

️ Episode 89: Decoding the Genetics of Smell: Sex-Specific Variants in Olfactory Identification In this episode of PaperCast Base by Base, we explore how...

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00:20:28

️ 88: Stable Heritability of Type 1 Diabetes Over Three Decades in Sweden

Episode 88

July 27, 2025

️ 88: Stable Heritability of Type 1 Diabetes Over Three Decades in Sweden

️ Episode 88: Stable Heritability of Type 1 Diabetes Over Three Decades in Sweden In this episode of PaperCast Base by Base, we explore...

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00:18:28

️ 87: Circulating cfDNA Methylation Reveals Allograft Injury Sources after Liver Transplant

Episode 87

July 26, 2025

️ 87: Circulating cfDNA Methylation Reveals Allograft Injury Sources after Liver Transplant

️ Episode 87: Circulating cfDNA Methylation Reveals Allograft Injury Sources after Liver Transplant In this episode of PaperCast Base by Base, we explore how...

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00:20:20

️ 86: Variable Penetrance in Monogenic Traits — How Genetic Background Modulates Disease Severity

Episode 86

July 25, 2025

️ 86: Variable Penetrance in Monogenic Traits — How Genetic Background Modulates Disease Severity

️ Episode 86: Variable Penetrance in Monogenic Traits — How Genetic Background Modulates Disease Severity In this episode of PaperCast Base by Base, we...

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00:19:27

️ 85: Genomic landscape of virus-associated cancers

Episode 85

July 24, 2025

️ 85: Genomic landscape of virus-associated cancers

️ Episode 85: Genomic landscape of virus-associated cancers In this episode of PaperCast Base by Base, we explore the comparative genomic analysis of virus-positive...

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00:23:15