Latest Episodes
Episode 218
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December 04, 2025
218: SIM1 and the multi-ancestry genomics of erectile dysfunction
Bright U et al., Nat Commun - A large multi-ancestry GWAS meta-analysis identifies a dominant SIM1-linked locus and multiple genetic connections between electronic health...
00:19:37
Episode 217
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December 03, 2025
217: Multiscale triads of meiotic crossover patterning
White MA et al., Nature Communications - FFT and inverse-FFT analysis of Zip3/Zip2, Hop1 and Zip1 on yeast pachytene chromosomes reveals two interdigitated tiers...
00:17:47
Episode 216
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December 02, 2025
216: 53BP1-RIF1 and DNA-PKcs: distinct interactions in chromosomal break repair
Makins K et al., Nature Communications - This episode reviews a study showing that 53BP1-RIF1 and DNA-PKcs have different genetic relationships across blunt end...
00:18:27
Episode 215
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December 01, 2025
215: Protein Set Transformer for high-diversity viromics
Martin et al., Nat Commun (2025) - Protein Set Transformer (PST) is a protein-based genome language model that represents genomes as sets of proteins...
00:20:07
Episode 214
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November 30, 2025
214: PI(4,5)P2 Asymmetry Accelerates FGF2 Secretion
Kaur M et al., Nature Communications - Reconstitution of asymmetric membranes and matched cell experiments show that transbilayer asymmetry of PI(4,5)P2 lowers the energetic...
00:18:21
Episode 213
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November 29, 2025
213: BRAIN-MAGNET: Functional genomics atlas for non-coding variants
Deng R et al. - BRAIN-MAGNET couples a ChIP-STARR-seq atlas of 148,198 neural regulatory elements with a validated convolutional neural network to predict enhancer...
00:20:29