Latest Episodes
Episode 5
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April 16, 2025
5: Promoter Footprints Predicting Preterm Birth
Guo Z et al., PLOS Medicine - Large multi-center case-control study shows promoter-region nucleosome footprints in plasma cell-free DNA can predict spontaneous preterm birth....
00:14:43
Episode 4
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April 16, 2025
4: How CXCL12 Shapes Coronary Dominance
Rios Coronado PE et al., Cell - A multi-ancestry GWAS in >61,000 veterans identifies CXCL12 as a top locus influencing whether the right or...
00:17:11
Episode 3
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April 16, 2025
3: Data-driven heuristics for splice-altering variants
Sullivan P et al., The American Journal of Human Genetics - A concise walkthrough of data-driven heuristics and a splicing checklist derived from large-scale...
00:22:42
Episode 2
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April 16, 2025
2: Tube additives and cfDNA integrity: why EDTA still leads
Barra G et al., LabMed (2025) 2, 4 - A comparative study of blood collection tubes (EDTA, citrate, heparin, serum) from 15 healthy volunteers...
00:16:23
Episode 1
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April 15, 2025
1: Structure-Informed Computational Evidence Sharpens BRCA1 Missense Classification
Ramadane-Morchadi L et al., The American Journal of Human Genetics - This episode reviews a study that evaluates how structure-based computational scores (AlphaMissense, FoldX...
00:20:25