Latest Episodes
August 04, 2025
️ 96: Early Cerebrospinal Fluid Proteomic Changes in Down Syndrome and Alzheimer’s Disease
️ Episode 96: Early Cerebrospinal Fluid Proteomic Changes in Down Syndrome and Alzheimer’s Disease In this episode of PaperCast Base by Base, we explore...
00:16:39
Episode 95
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August 03, 2025
95: Mitochondria transfer: biotech strategies and clinical hurdles
Kubat GB et al., Nature Communications - This Perspective surveys recent biotechnological advances that enhance mitochondria transfer and transplantation (MTT) — including surface functionalization,...
00:19:10
Episode 94
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August 02, 2025
94: Intraindividual epigenetic heterogeneity in advanced prostate cancer
Mizuno K et al., Nature Communications - Multi-omic profiling (DNA methylation, RNA-seq, H3K27ac and H3K27me3) of 98 metastatic CRPC samples from 35 patients reveals...
00:20:29
Episode 93
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August 01, 2025
93: Bovine H5N1 Shows Neurovirulence in Mice
Tipih T et al., Nature Communications - Comparative mouse study finds a dairy-cow-derived H5N1 clade 2.3.4.4b (genotype B3.13) isolate is highly virulent, producing rapid...
00:19:01
Episode 92
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July 31, 2025
92: Loss of CFHR5 Function Lowers AMD Risk
Nature Communications - A FinnGen-based genetic and functional study identifies CFHR5 loss-of-function variants as independently protective against age-related macular degeneration and links reduced FHR-5...
00:16:49
Episode 91
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July 30, 2025
91: Plasma N‑Glycome, Liver Disease & Anti‑inflammatory Proteins
Sharapov S et al., Nature Communications - This episode examines a large multi-cohort GWAS of the human plasma N-glycome (N≈10,764) that maps genetic regulation...
00:17:42