Latest Episodes
Episode 214
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November 30, 2025
214: PI(4,5)P2 Asymmetry Accelerates FGF2 Secretion
Kaur M et al., Nature Communications - Reconstitution of asymmetric membranes and matched cell experiments show that transbilayer asymmetry of PI(4,5)P2 lowers the energetic...
00:18:21
Episode 213
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November 29, 2025
213: BRAIN-MAGNET: Functional genomics atlas for non-coding variants
Deng R et al. - BRAIN-MAGNET couples a ChIP-STARR-seq atlas of 148,198 neural regulatory elements with a validated convolutional neural network to predict enhancer...
00:20:29
Episode 212
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November 28, 2025
212: Zonal control of mutant β-catenin tumorigenesis
Raven A et al. - This study shows that hepatic zonation determines whether mutant β-catenin drives proliferation and liver cancer by forcing differentiation to...
00:16:47
Episode 211
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November 27, 2025
211: Retention Elements in Cancer Cells
Sankar et al. - This episode explores the discovery of genetic elements that promote the retention of extrachromosomal DNA (ecDNA) in cancer cells, enhancing...
00:19:30
Episode 210
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November 26, 2025
210: Tumour-Reactive CD8 T Cell Clusters in Human Melanoma
Tumour-Reactive CD8 T Cell Clusters in Human Melanoma Music:Enjoy the music based on this article at the end of the episode. DOI:10.1038/s41586-025-09754-w License:This episode...
00:18:45
Episode 209
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November 25, 2025
209: PERT: Prime Editing tRNAs for Nonsense Mutations
PERT: Prime Editing tRNAs for Nonsense Mutations Music:Enjoy the music based on this article at the end of the episode. DOI:10.1038/s41586-025-09732-2 License:This episode is...
00:16:54