Latest Episodes
Episode 54
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June 24, 2025
54: Immune trajectories in COVID-19 among patients with end-stage kidney disease
Stephenson E et al., Cell Genomics - Longitudinal single-cell multi-omics profiling of PBMCs from 61 end-stage kidney disease (ESKD) patients with COVID-19 (580,040 cells)...
00:18:50
Episode 53
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June 23, 2025
53: Weighing PRS: costs, benefits, and evidence
Siena LM et al., The American Journal of Human Genetics - A systematic review of 24 full economic evaluations assessing polygenic risk score (PRS)–based...
00:17:13
Episode 52
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June 22, 2025
52: LIZS6 methods and measurements
Keener R et al., Cell Genomics - A method-focused excerpt describing LIZS6-related experiments across multiple conditions (NoSk, LSFM) with quantitative readouts and protocol detail....
00:16:43
Episode 51
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June 21, 2025
51: Finding Hidden mtDNA Diagnoses in Solve-RD
Ratnaike et al et al., The American Journal of Human Genetics - This episode reviews a Solve-RD reanalysis that integrated an mtDNA-focused bioinformatic pipeline...
00:17:38
Episode 50
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June 19, 2025
50: Translating the Microbiome to the Clinic
Porcari S et al., Cell - Perspective reviewing current diagnostic and therapeutic advances in gut microbiome research and outlining the methodological, biological, regulatory, and...
00:17:57
Episode 49
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June 18, 2025
49: Chitin as a reservoir: DNA adsorption and gene transfer in Vibrio cholerae
Holt JD et al., PNAS - Using microfluidic flow assays and live-cell imaging, the authors show that environmental DNA adsorbs to chitin particles and...
00:22:59