Latest Episodes
Episode 132
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September 09, 2025
132: Transcriptome classifiers predict docetaxel sensitivity in advanced prostate cancer
Grist E et al., Cell - Large-scale transcriptome profiling of 1,523 diagnostic prostate tumors from randomized STAMPEDE phase 3 trials linked expression signatures and...
00:20:35
Episode 131
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September 08, 2025
131: Cryptic plasmid pBI143: a small element with outsized presence in the human gut
Fogarty EC et al., Cell (187:1206–1222, February 29, 2024) - This episode summarizes Fogarty et al. 2024, which characterizes pBI143, a 2.7 kb cryptic...
00:17:59
Episode 130
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September 07, 2025
130: Genetics + CRISPR to Map Obesity and Fat Distribution
Baya NA et al., The American Journal of Human Genetics - This episode summarizes a multi-modal study that integrates exome sequencing in 402,375 UK...
00:20:24
Episode 129
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September 06, 2025
129: NPIP — Structural variation, selection, and paralog diversification
Dishuck PC et al., Cell Genomics - Using 169 long-read human haplotypes and 1.4 billion full-length cDNA reads, Dishuck et al. resolve the complex...
00:22:11
Episode 128
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September 05, 2025
128: L1 elements, chromatin and CRISPRi
Adami A et al., Cell Genomics - This episode covers analyses of L1 retrotransposon subfamilies (L1PA2/3/4, L1HS), their chromatin signatures (including H3K4me3), and perturbation...
00:15:26
Episode 127
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September 04, 2025
127: OncoGAN: Generating Synthetic Cancer Genomes with AI
Díaz-Navarro A et al., Cell Genomics - OncoGAN is a multimodel generative AI pipeline that simulates realistic, privacy-preserving cancer genomes (VCFs, CNAs, SVs) across...
00:17:36