Latest Episodes
Episode 129
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September 06, 2025
129: NPIP — Structural variation, selection, and paralog diversification
Dishuck PC et al., Cell Genomics - Using 169 long-read human haplotypes and 1.4 billion full-length cDNA reads, Dishuck et al. resolve the complex...
00:22:11
Episode 128
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September 05, 2025
128: L1 elements, chromatin and CRISPRi
Adami A et al., Cell Genomics - This episode covers analyses of L1 retrotransposon subfamilies (L1PA2/3/4, L1HS), their chromatin signatures (including H3K4me3), and perturbation...
00:15:26
Episode 127
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September 04, 2025
127: OncoGAN: Generating Synthetic Cancer Genomes with AI
Díaz-Navarro A et al., Cell Genomics - OncoGAN is a multimodel generative AI pipeline that simulates realistic, privacy-preserving cancer genomes (VCFs, CNAs, SVs) across...
00:17:36
Episode 126
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September 03, 2025
126: Smith-Magenis Syndrome: Chromatin Rewiring to Hyperexcitable Neurons
Lee Y et al., The American Journal of Human Genetics - This episode reviews a study using hiPSC-derived 2D cortical neurons and 3D cortical...
00:20:59
Episode 125
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September 02, 2025
125: GP2: A Global Roadmap for Parkinson’s Genetics
Blauwendraat C et al., The American Journal of Human Genetics - This episode reviews a perspective on the Global Parkinson’s Genetics Program (GP2), a...
00:22:46
Episode 124
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September 01, 2025
124: Omnigenic Architecture and Core Genes in Ulcerative Colitis
Ratajczak F et al., The American Journal of Human Genetics - This study uses the Speos graph machine-learning framework on multi-modal molecular networks to...
00:23:47