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Base by Base

Base by Base explores advances in genetics and genomics, with a focus on gene-disease associations, variant interpretation, protein structure, and insights from exome and genome sequencing. Each episode breaks down key studies and their clinical...more

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Latest Episodes

185: Altered Milk Tryptophan in Women Living with HIV

Episode 185

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November 01, 2025

185: Altered Milk Tryptophan in Women Living with HIV

️ Episode 185: Altered Milk Tryptophan in Women Living with HIV In this episode of PaperCast Base by Base, we explore a longitudinal metabolomics...

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00:14:59

184: High-Accuracy Multiethnic XGBoost for Skin Cancer Identification

Episode 184

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October 31, 2025

184: High-Accuracy Multiethnic XGBoost for Skin Cancer Identification

️ Episode 184: High-Accuracy Multiethnic XGBoost for Skin Cancer Identification In this episode of PaperCast Base by Base, we explore a large-scale study that...

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00:17:44

183: The Genetic Lottery Goes to School: Better Schools Compensate for Genetic Differences

Episode 183

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October 30, 2025

183: The Genetic Lottery Goes to School: Better Schools Compensate for Genetic Differences

️ Episode 183: The Genetic Lottery Goes to School: Better Schools Compensate for Genetic Differences In this episode of PaperCast Base by Base, we...

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00:18:05

182: Genotypic, Functional, and Phenotypic Characterization in CTNNB1 Neurodevelopmental Syndrome

Episode 182

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October 29, 2025

182: Genotypic, Functional, and Phenotypic Characterization in CTNNB1 Neurodevelopmental Syndrome

️ Episode 182: Genotypic, Functional, and Phenotypic Characterization in CTNNB1 Neurodevelopmental Syndrome In this episode of PaperCast Base by Base, we explore a large...

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00:16:18

181: Creatine Transporter SLC6A8: Conservation and Variant Impact

Episode 181

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October 28, 2025

181: Creatine Transporter SLC6A8: Conservation and Variant Impact

️ Episode 181: Creatine Transporter SLC6A8: Conservation and Variant Impact In this episode of PaperCast Base by Base, we explore how the creatine transporter...

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00:12:44

180: Leveraging Global Genetics Resources for Equitable Polygenic Prediction

Episode 180

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October 27, 2025

180: Leveraging Global Genetics Resources for Equitable Polygenic Prediction

️ Episode 180: Leveraging Global Genetics Resources for Equitable Polygenic Prediction In this episode of PaperCast Base by Base, we explore how multi-ancestry genome-wide...

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00:22:11